Studies show that foot reflexology may cause fatigue in some individuals, but this is often temporary and a natural part of the healing process. The causes may include pre-existing conditions or hormonal imbalances that affect energy levels. Emotional releases and stress relief during treatment can also contribute to fatigue. Physical factors such as weakened muscles or poor posture can further impact energy levels. Case studies demonstrate successful therapeutic uses, including pain management, inflammation reduction, and blood pressure control. Mental benefits include improved mood stabilization, cognitive function enhancement, and reduced anxiety.